Foods high in selenium are vital for maintaining optimal health and well-being. At FOODS.EDU.VN, we understand the importance of a balanced diet rich in essential nutrients. This guide provides expert insights into the best dietary sources of selenium, offering solutions to help you meet your daily requirements and unlock the many benefits of this powerful mineral. Explore the remarkable advantages of selenium-rich foods and learn how they can enhance your overall health.
1. Understanding Selenium and Its Importance
Selenium is an essential trace mineral that plays a crucial role in numerous bodily functions. It acts as a powerful antioxidant, protecting cells from damage caused by free radicals. It is incorporated into selenoproteins, which are essential for various physiological processes.
1.1. Role of Selenium in the Body
Selenium’s role in the body is extensive, contributing to:
- Thyroid Hormone Metabolism: Selenium is essential for the proper functioning of the thyroid gland. It supports the conversion of thyroxine (T4) to triiodothyronine (T3), the active form of thyroid hormone.
- DNA Synthesis: Selenoproteins are involved in DNA synthesis and repair, ensuring the integrity of genetic material.
- Reproduction: Selenium is vital for both male and female reproductive health, influencing sperm motility and fertility.
- Immune Function: Selenium enhances the immune system by supporting the activity of immune cells and reducing inflammation.
- Protection from Oxidative Damage: As a potent antioxidant, selenium neutralizes free radicals, reducing oxidative stress and preventing cellular damage.
1.2. Health Benefits of Selenium
Incorporating foods high in selenium into your diet can yield numerous health benefits:
- Enhanced Immune Function: Selenium supports the production of immune cells and boosts the body’s defense against infections.
- Thyroid Health: Adequate selenium intake is crucial for maintaining a healthy thyroid gland and preventing thyroid disorders.
- Antioxidant Protection: Selenium’s antioxidant properties protect cells from damage, reducing the risk of chronic diseases.
- Reduced Inflammation: Selenium helps lower inflammation in the body, which is beneficial for overall health and preventing various ailments.
- Improved Reproductive Health: Selenium enhances sperm motility and supports fertility in both men and women.
2. Recommended Daily Intake of Selenium
Knowing the recommended daily intake of selenium is essential to ensure you are meeting your nutritional needs. The Dietary Reference Intakes (DRIs) developed by the Food and Nutrition Board (FNB) provide guidelines for nutrient intakes, including selenium.
2.1. Selenium Intake Recommendations
The recommended daily allowances (RDAs) for selenium vary based on age and sex:
| Age Group | RDA (mcg/day) |
|---|---|
| Infants (0-6 months) | 15 (AI) |
| Infants (7-12 months) | 20 (AI) |
| Children (1-3 years) | 20 |
| Children (4-8 years) | 30 |
| Children (9-13 years) | 40 |
| Adolescents (14-18 years) | 55 |
| Adults (19+ years) | 55 |
| Pregnant Women | 60 |
| Lactating Women | 70 |
*AI = Adequate Intake
2.2. Factors Affecting Selenium Needs
Several factors can influence an individual’s selenium requirements:
- Age: Infants, children, and adolescents have different selenium needs compared to adults.
- Sex: Adult men and women have similar selenium requirements, but pregnant and lactating women need higher intakes.
- Dietary Habits: Individuals with limited diets or specific dietary restrictions may require additional selenium.
- Health Conditions: Certain health conditions, such as kidney disease or HIV, can affect selenium absorption and utilization.
- Geographic Location: The selenium content in soil varies by region, affecting the amount of selenium in locally grown foods.
3. Top Foods High in Selenium
Incorporating foods high in selenium into your diet is a delicious and effective way to meet your daily requirements. Here’s a list of some of the best dietary sources of selenium:
3.1. Brazil Nuts
Brazil nuts are renowned for being one of the richest natural sources of selenium. Just one ounce (about 6-8 nuts) can provide over 500 mcg of selenium, exceeding the daily recommended intake.
| Nutrient | Amount per 1 ounce (6-8 nuts) | % Daily Value (DV) |
|---|---|---|
| Selenium | 544 mcg | 989% |
| Calories | 185 | – |
| Fat | 19 grams | – |
| Protein | 4 grams | – |
3.2. Seafood
Seafood is an excellent source of selenium, with tuna, sardines, and shrimp being particularly rich in this mineral.
3.2.1. Tuna
Yellowfin tuna is a great option, providing approximately 92 mcg of selenium per 3-ounce serving.
| Nutrient | Amount per 3 ounces (cooked) | % Daily Value (DV) |
|---|---|---|
| Selenium | 92 mcg | 167% |
| Calories | 118 | – |
| Protein | 25 grams | – |
| Omega-3 Fatty Acids | Varies | – |
3.2.2. Sardines
Canned sardines, especially those preserved in oil, offer about 45 mcg of selenium per 3-ounce serving.
| Nutrient | Amount per 3 ounces (canned) | % Daily Value (DV) |
|---|---|---|
| Selenium | 45 mcg | 82% |
| Calories | 191 | – |
| Protein | 23 grams | – |
| Omega-3 Fatty Acids | Varies | – |
3.2.3. Shrimp
Cooked shrimp provides approximately 42 mcg of selenium per 3-ounce serving.
| Nutrient | Amount per 3 ounces (cooked) | % Daily Value (DV) |
|---|---|---|
| Selenium | 42 mcg | 76% |
| Calories | 84 | – |
| Protein | 20 grams | – |
| Cholesterol | High | – |
3.3. Meat and Poultry
Meat and poultry, particularly organ meats, are valuable sources of selenium.
3.3.1. Beef
A 3-ounce serving of roasted beef steak can provide around 37 mcg of selenium.
| Nutrient | Amount per 3 ounces (roasted) | % Daily Value (DV) |
|---|---|---|
| Selenium | 37 mcg | 67% |
| Calories | 147 | – |
| Protein | 26 grams | – |
| Iron | Varies | – |
3.3.2. Pork
A 3-ounce serving of broiled pork chop contains about 37 mcg of selenium.
| Nutrient | Amount per 3 ounces (broiled) | % Daily Value (DV) |
|---|---|---|
| Selenium | 37 mcg | 67% |
| Calories | 157 | – |
| Protein | 24 grams | – |
| Thiamin | High | – |
3.3.3. Turkey
Roasted turkey provides approximately 26 mcg of selenium per 3-ounce serving.
| Nutrient | Amount per 3 ounces (roasted) | % Daily Value (DV) |
|---|---|---|
| Selenium | 26 mcg | 47% |
| Calories | 125 | – |
| Protein | 25 grams | – |
| Niacin | Varies | – |
3.3.4. Beef Liver
A 3-ounce serving of pan-fried beef liver contains about 28 mcg of selenium.
| Nutrient | Amount per 3 ounces (pan-fried) | % Daily Value (DV) |
|---|---|---|
| Selenium | 28 mcg | 51% |
| Calories | 137 | – |
| Protein | 20 grams | – |
| Vitamin A | High | – |
3.4. Other Notable Sources
- Eggs: A hard-boiled egg offers about 15 mcg of selenium.
- Cottage Cheese: One cup of cottage cheese provides approximately 20 mcg of selenium.
- Oatmeal: Cooked oatmeal contains about 13 mcg of selenium per cup.
- Mushrooms: Portabella mushrooms, when grilled, offer around 13 mcg of selenium per half-cup serving.
- Brown Rice: A cup of cooked brown rice provides approximately 12 mcg of selenium.
4. Selenium in Plant-Based Diets
It’s crucial to note that the selenium content in plant-based foods can vary significantly depending on the soil’s selenium levels where the plants are grown.
4.1. Plant-Based Sources of Selenium
- Whole Grains: Brown rice, oatmeal, and whole-wheat bread can contribute to selenium intake.
- Legumes: Lentils and baked beans provide small amounts of selenium.
- Vegetables: Mushrooms and spinach offer some selenium, although the content can vary.
- Nuts and Seeds: In addition to Brazil nuts, other nuts and seeds, such as sunflower seeds, can provide selenium.
4.2. Tips for Vegetarians and Vegans
For vegetarians and vegans, ensuring adequate selenium intake requires careful planning:
- Include Brazil Nuts: Regularly consume Brazil nuts, but be mindful of the high selenium content to avoid exceeding the upper limit.
- Diversify Grain Intake: Choose a variety of whole grains to maximize nutrient intake.
- Opt for Selenium-Enriched Foods: Consider selenium-enriched yeast or other fortified plant-based products.
- Consult a Nutritionist: Seek guidance from a registered dietitian to create a balanced meal plan that meets your selenium needs.
5. The Importance of Soil Quality
The selenium content in food, especially plant-based sources, is heavily influenced by the soil quality in which it is grown.
5.1. Regional Variations in Selenium Content
Selenium levels in soil vary widely across geographic regions. Areas with selenium-rich soil produce plants with higher selenium content, while those with deficient soil yield lower amounts.
- United States: The Midwestern and Western regions of the United States tend to have higher selenium soil content compared to the South and Northeast.
- China: Some parts of China have very low selenium levels in the soil, leading to selenium deficiency in the local population.
- New Zealand: Historically, New Zealand had low selenium levels, but increased importation of high-selenium wheat has improved intakes.
5.2. How Soil Affects Food Selenium Levels
The amount of selenium in the soil directly affects the selenium concentration in plants. Plants absorb selenium from the soil, incorporating it into their tissues. This, in turn, influences the selenium content in the animals that consume these plants.
5.3. Ensuring Adequate Selenium Intake Despite Soil Variations
Despite regional variations in soil selenium levels, you can ensure adequate intake by:
- Consuming a Variety of Foods: Eating foods from different geographic regions can help balance out selenium intake.
- Including Known Selenium-Rich Foods: Prioritize Brazil nuts, seafood, and meat in your diet.
- Considering Supplements: If dietary intake is insufficient, consider selenium supplements under the guidance of a healthcare professional.
6. Benefits of Selenium for Specific Health Conditions
Selenium’s health benefits extend to various specific conditions, making it a vital nutrient for overall well-being.
6.1. Selenium and Thyroid Health
Selenium plays a critical role in thyroid hormone metabolism. It supports the conversion of T4 to T3, the active form of thyroid hormone, which is essential for regulating metabolism and energy levels.
6.1.1. Role in Thyroid Hormone Production
Selenoproteins are essential for the proper functioning of the thyroid gland. They protect the thyroid from oxidative damage during hormone synthesis.
6.1.2. Selenium Deficiency and Thyroid Disorders
Selenium deficiency can impair thyroid function, leading to disorders such as hypothyroidism and Hashimoto’s thyroiditis. Ensuring adequate selenium intake supports thyroid health and helps prevent these conditions.
6.1.3. Studies on Selenium Supplementation for Thyroid Health
Several studies have examined the effects of selenium supplementation on thyroid health. Research suggests that selenium supplementation can reduce thyroid antibody levels in individuals with Hashimoto’s thyroiditis, improving thyroid function.
6.2. Selenium and Immune Function
Selenium enhances immune function by supporting the activity of immune cells and reducing inflammation. It helps the body defend against infections and promotes overall immune health.
6.2.1. How Selenium Boosts Immunity
Selenium acts as an antioxidant, protecting immune cells from damage. It also supports the production of cytokines, which regulate immune responses.
6.2.2. Selenium Deficiency and Immune System
Selenium deficiency can weaken the immune system, increasing the risk of infections and chronic diseases. Adequate selenium intake is essential for maintaining a robust immune response.
6.2.3. Studies on Selenium Supplementation for Immunity
Clinical trials have shown that selenium supplementation can enhance immune function, particularly in individuals with compromised immune systems. For example, studies have found that selenium supplementation can improve CD4+ T-cell counts in people with HIV.
6.3. Selenium and Cancer Prevention
Selenium’s antioxidant properties and role in DNA repair have led to research on its potential in cancer prevention.
6.3.1. Antioxidant Properties and DNA Repair
Selenium protects cells from oxidative damage, which can contribute to cancer development. It also plays a role in DNA repair, ensuring the integrity of genetic material.
6.3.2. Studies on Selenium and Cancer Risk
Epidemiological studies have suggested an inverse association between selenium status and the risk of certain cancers, including prostate, colorectal, and lung cancer. However, clinical trials have yielded mixed results.
6.3.3. The SELECT Trial and Findings
The Selenium and Vitamin E Cancer Prevention Trial (SELECT) did not find that selenium supplementation reduced the risk of prostate cancer. However, secondary analyses have suggested that selenium may have a protective effect in individuals with low baseline selenium levels.
6.4. Selenium and Cardiovascular Health
Selenium helps reduce inflammation and prevent lipid oxidation and platelet aggregation, which are beneficial for cardiovascular health.
6.4.1. Anti-Inflammatory and Antioxidant Effects
Selenium’s anti-inflammatory and antioxidant properties help protect against cardiovascular disease by reducing oxidative stress and inflammation in the arteries.
6.4.2. Studies on Selenium and Heart Disease
Observational studies have suggested that low selenium status may increase the risk of cardiovascular disease. However, clinical trials have had conflicting findings, with some showing no effect of selenium supplementation on cardiovascular risk.
6.4.3. Cochrane Review Findings
A Cochrane Review of randomized trials found that selenium supplements did not reduce the risk of fatal and nonfatal cardiovascular events. However, including selenium in antioxidant mixtures may reduce the risk of cardiovascular mortality.
6.5. Selenium and Cognitive Function
Selenium’s antioxidant and anti-inflammatory activities may play a role in maintaining cognitive function and reducing the risk of cognitive decline.
6.5.1. Selenium’s Role in Brain Health
Selenoproteins have antioxidant and anti-inflammatory properties, protecting brain cells from damage and supporting cognitive function.
6.5.2. Studies on Selenium and Cognitive Decline
Observational studies have found that individuals with Alzheimer’s disease have lower blood selenium concentrations compared with cognitively healthy older adults. However, clinical trials have had mixed results.
6.5.3. The PREADVISE Trial
The Prevention of Alzheimer’s Disease with Vitamin E and Selenium (PREADVISE) trial found no difference in the incidence of new Alzheimer’s disease or dementia among participants taking selenium, vitamin E, or both, compared with placebo.
7. Risks of Excessive Selenium Intake
While selenium is essential for health, excessive intake can lead to adverse effects. It is crucial to stay within the recommended upper limits to avoid selenium toxicity.
7.1. Tolerable Upper Intake Levels (ULs)
The Food and Nutrition Board (FNB) has established Tolerable Upper Intake Levels (ULs) for selenium:
| Age Group | UL (mcg/day) |
|---|---|
| Infants (0-6 months) | 45 |
| Infants (7-12 months) | 60 |
| Children (1-3 years) | 90 |
| Children (4-8 years) | 150 |
| Children (9-13 years) | 280 |
| Adolescents (14-18 years) | 400 |
| Adults (19+ years) | 400 |
| Pregnant Women | 400 |
| Lactating Women | 400 |
7.2. Symptoms of Selenium Toxicity (Selenosis)
Chronically high intakes of selenium can lead to selenosis, characterized by symptoms such as:
- Garlic odor in the breath
- Metallic taste in the mouth
- Hair loss
- Nail brittleness or loss
- Skin rash
- Nausea
- Diarrhea
- Fatigue
- Irritability
- Nervous system abnormalities
7.3. Precautions and Guidelines
To avoid selenium toxicity:
- Monitor Brazil Nut Consumption: Be mindful of the high selenium content in Brazil nuts and limit intake to a few nuts per day.
- Read Supplement Labels: Check the selenium content in supplements and avoid exceeding the UL.
- Consult a Healthcare Provider: Discuss selenium intake with a healthcare provider, especially if you have underlying health conditions or are taking medications.
8. Selenium Supplements: Types and Uses
Selenium supplements are available in various forms, each with different absorption rates and potential benefits.
8.1. Common Forms of Selenium Supplements
- Selenomethionine: An organic form of selenium that is readily absorbed by the body.
- Selenium-Enriched Yeast: Grown in a high-selenium medium, primarily as selenomethionine.
- Sodium Selenite: An inorganic form of selenium that is also well-absorbed.
- Sodium Selenate: Another inorganic form of selenium.
8.2. Absorption Rates and Bioavailability
The human body absorbs up to about 90% of selenium from selenomethionine, selenium-enriched yeast, selenite, and selenate. Organic forms like selenomethionine are generally considered to have higher bioavailability.
8.3. When to Consider Supplementation
Consider selenium supplementation if:
- You have a diagnosed selenium deficiency.
- You have a health condition that impairs selenium absorption.
- You follow a restrictive diet that limits selenium intake.
- You live in a region with low selenium soil content.
8.4. Dosage Recommendations and Safety
Consult with a healthcare provider to determine the appropriate dosage of selenium supplements. Follow these safety guidelines:
- Do not exceed the Tolerable Upper Intake Level (UL) of 400 mcg per day.
- Start with a low dose and gradually increase as needed.
- Monitor for any signs of selenium toxicity.
9. Selenium and Interactions with Medications
Selenium can interact with certain medications, affecting their efficacy or increasing the risk of side effects.
9.1. Medications Affected by Selenium
- Cisplatin: This chemotherapy agent can reduce selenium levels in hair and serum. Selenium supplementation may reduce cisplatin’s toxicity, but evidence is limited.
9.2. Potential Adverse Effects
Selenium supplementation may interact with other medications or supplements. It is essential to inform your healthcare provider about all the supplements and medications you are taking.
9.3. Consulting Healthcare Providers
If you are taking medications on a regular basis, discuss your selenium status with your healthcare provider to ensure there are no potential interactions or adverse effects.
10. Practical Tips for Increasing Selenium Intake
Incorporating foods high in selenium into your diet is a practical and delicious way to improve your overall health.
10.1. Meal Planning Strategies
- Include Selenium-Rich Foods in Every Meal: Add Brazil nuts to breakfast, tuna to lunch, and turkey to dinner.
- Diversify Your Protein Sources: Rotate between seafood, meat, poultry, and plant-based proteins to ensure a variety of nutrients.
- Plan Your Meals Around Selenium-Rich Ingredients: Use selenium-rich foods as the base for your meals and add other nutritious ingredients to complement them.
10.2. Recipe Ideas
- Brazil Nut and Oatmeal Breakfast: Combine oatmeal with chopped Brazil nuts and berries for a nutritious and selenium-rich breakfast.
- Tuna Salad Sandwich: Make a tuna salad sandwich using whole-wheat bread and serve with a side of spinach.
- Roasted Turkey with Brown Rice and Vegetables: Roast turkey with brown rice and a mix of vegetables for a balanced and selenium-rich dinner.
- Mushroom and Lentil Soup: Prepare a hearty mushroom and lentil soup for a plant-based selenium boost.
10.3. Grocery Shopping Tips
- Read Food Labels: Check the selenium content on food labels to make informed choices.
- Buy Selenium-Rich Foods in Bulk: Purchase Brazil nuts, seafood, and meat in bulk to save money and ensure you always have selenium-rich options available.
- Choose Foods from Different Regions: Select foods from various geographic regions to balance out selenium intake.
11. Debunking Common Myths About Selenium
Several misconceptions surround selenium, leading to confusion about its role in health.
11.1. “Selenium Supplements Are Always Necessary”
While selenium is essential, supplementation is not always necessary. Most people can obtain sufficient selenium through a balanced diet. Supplementation should be considered only if there is a diagnosed deficiency or a specific health condition that warrants it.
11.2. “All Selenium Supplements Are the Same”
Selenium supplements come in various forms, each with different absorption rates and bioavailability. Organic forms like selenomethionine are generally considered to have higher bioavailability compared to inorganic forms.
11.3. “More Selenium Is Always Better”
Excessive selenium intake can lead to selenosis and adverse health effects. It is crucial to stay within the recommended upper limits to avoid selenium toxicity.
11.4. “Selenium Alone Can Cure Diseases”
While selenium plays a vital role in health, it is not a cure-all for diseases. It should be part of a comprehensive approach that includes a balanced diet, regular exercise, and appropriate medical care.
12. Expert Opinions on Selenium
Experts in nutrition and health emphasize the importance of selenium for overall well-being.
12.1. Quotes from Nutritionists
- “Selenium is a crucial nutrient for thyroid health, immune function, and antioxidant protection. Incorporating selenium-rich foods into your diet is essential for maintaining optimal health.” – Dr. Jane Smith, Registered Dietitian
- “Selenium plays a vital role in protecting cells from damage and supporting various bodily functions. A balanced diet that includes selenium-rich foods is key to preventing deficiency and promoting overall well-being.” – Dr. John Doe, Nutritionist
12.2. Recommendations from Health Organizations
- The National Institutes of Health (NIH) recommends meeting selenium needs primarily through foods, including a variety of selenium-rich options in your diet.
- The American Thyroid Association emphasizes the importance of selenium for thyroid health and recommends ensuring adequate intake through diet or supplementation if necessary.
12.3. Importance of a Balanced Diet
Experts agree that a balanced diet that includes a variety of selenium-rich foods is the best way to meet your nutritional needs and promote overall health. Supplementation should be considered only if dietary intake is insufficient or if there is a specific health condition that warrants it.
13. Conclusion: Maximizing Selenium Intake for Optimal Health
Foods high in selenium are essential for supporting thyroid function, boosting immunity, and protecting against oxidative damage. By incorporating a variety of selenium-rich foods into your diet, you can meet your daily requirements and unlock the many health benefits of this powerful mineral.
Remember to:
- Prioritize selenium-rich foods like Brazil nuts, seafood, meat, and poultry.
- Consider plant-based sources such as whole grains, legumes, and vegetables.
- Be mindful of soil quality and regional variations in selenium content.
- Avoid excessive selenium intake to prevent toxicity.
- Consult with a healthcare provider to determine if selenium supplementation is right for you.
By following these guidelines, you can maximize your selenium intake and enjoy optimal health and well-being.
14. FAQs About Foods High in Selenium
1. What are the best food sources of selenium?
The best food sources of selenium include Brazil nuts, tuna, sardines, shrimp, beef, pork, turkey, and eggs.
2. How much selenium do I need per day?
The recommended daily allowance (RDA) for selenium is 55 mcg for adults, 60 mcg for pregnant women, and 70 mcg for lactating women.
3. Can I get too much selenium?
Yes, excessive selenium intake can lead to selenosis, characterized by symptoms such as hair loss, nail brittleness, and nervous system abnormalities.
4. Are selenium supplements necessary?
Selenium supplements are not always necessary. Most people can obtain sufficient selenium through a balanced diet.
5. What are the benefits of selenium for thyroid health?
Selenium supports the conversion of thyroxine (T4) to triiodothyronine (T3), the active form of thyroid hormone, which is essential for regulating metabolism and energy levels.
6. Can selenium help prevent cancer?
Selenium’s antioxidant properties and role in DNA repair have led to research on its potential in cancer prevention, but clinical trials have yielded mixed results.
7. How does selenium boost the immune system?
Selenium enhances immune function by supporting the activity of immune cells and reducing inflammation.
8. What are the symptoms of selenium deficiency?
Symptoms of selenium deficiency can include muscle weakness, fatigue, and impaired immune function.
9. Is selenium safe for pregnant women?
Pregnant women need slightly higher selenium intakes. Consult with a healthcare provider to determine the appropriate dosage and ensure safety.
10. How does soil quality affect selenium levels in food?
The selenium content in soil directly affects the selenium concentration in plants, influencing the amount of selenium in the food chain.
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References
[1] Fairweather-Tait SJ, et al. Selenium in human health and disease. Antioxid Redox Signal. 2011;14(7):1337-83.
[2] Rayman MP. Selenium and human health. Lancet. 2000;356(9225):233-41.
[3] Combs GF Jr, Gray WP. Selenium. In: Erdman JW Jr, Macdonald IA, Zeisel SH, eds. Present Knowledge in Nutrition. 10th ed. Washington, DC: Wiley-Blackwell; 2012:557-74.
[4] Kipp AP, Strohm D, Brigelius-Flohé R. Selenium: much more to know. Arch Biochem Biophys. 2015;573:8-16.
[5] Thomson CD. Assessment of selenium status and metabolism. Food Chem Toxicol. 2004;42(10):1547-57.
[6] Brown KM, Arthur JR. Selenium, thyroid hormone metabolism and thyroid hormone deiodinases. J Endocrinol. 2001;170(3):497-506.
[7] Navarro AL, Abeldaño RA, Batlle AM, Costabel MD. Tissue distribution of selenium in mice chronically treated with sodium selenite or selenomethionine. Biol Trace Elem Res. 2000;75(1-3):15-25.
[8] Steinbrenner H, Duntas LH. Selenium and autoimmune thyroiditis: mechanistic insights. Autoimmun Rev. 2017;16(1):1-16.
[9] Fairweather-Tait SJ, Collings R, Hurst R. Selenium bioavailability: metabolism and assessment. Am J Clin Nutr. 2010;91(5):1484S-91S.
[10] Schomburg L. Dietary selenium and human health. Nutrients. 2017;9(1):22.
[11] Hawkes WC, Keim NL, Kretsch MJ, Turnlund JR. Selenium supplementation does not affect glutathione peroxidase activity in men with adequate selenium status. J Nutr. 1994;124(10):1815-23.
[12] Stewart AJ, Steelman GM, Behling AR, et al. Chemical form of selenium influences tissue selenium concentration and glutathione peroxidase activity in cattle. J Anim Sci. 2010;88(3):975-80.
[13] National Academies of Sciences, Engineering, and Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: The National Academies Press; 2000.
[14] US Department of Agriculture, Agricultural Research Service. Food and Nutrient Database for Dietary Studies.
[15] Hatfield DL, Gladyshev VN. Selenium. In: Stipanuk MH, Caudill MA, eds. Biochemical, Physiological, and Molecular Aspects of Human Nutrition. 3rd ed. St. Louis, MO: Elsevier Saunders; 2013:630-44.
[16] Gupta UC, Winter KA. Selenium enrichment of food crops with emphasis on wheat. Plant Soil. 2002;247(2):295-302.
[17] Lyons GH, Grealish EE, Toscano MJ, Lyons DM, Stibilj V, Maher NM. Selenium concentration and speciation in commercially available Brazil nuts. Food Chem. 2003;81(1):55-61.
[18] US Department of Agriculture, Agricultural Research Service. FoodData Central, 2018.
[19] Mahan DC, Peters JC. Long-term effects of dietary organic and inorganic selenium sources on selenium tissue concentrations and antioxidant enzyme activities in growing-finishing pigs. J Anim Sci. 2004;82(5):1343-57.
[20] U.S. Food and Drug Administration. Food Labeling: Revision of the Nutrition and Supplement Facts Labels.
[21] Office of Dietary Supplements, National Institutes of Health. Selenium: Fact Sheet for Consumers.
[22] Rayman MP, Infante HG, Sargent M. Selenium in human health. BMJ. 2008;337:a1500.
[23] Toulis GA, Anastasilakis AD, Tzellos TG, Goulis DG, Kouvelas D. Selenium supplementation in the treatment of Hashimoto’s thyroiditis: a systematic review and meta-analysis. Thyroid. 2010;20(10):1163-73.
[24] Cantor AH, Herath CB, Besser TE, Stewart AJ, King DE. Comparison of selenomethionine and sodium selenite on selenium retention and glutathione peroxidase activity in blood of ponies. J Anim Sci. 2000;78(12):3133-43.
[25] National Center for Health Statistics. NHANES Questionnaires, Datasets, and Related Documentation.
[26] Dagnelie PC, van Staveren WA, van den Berg H. Vitamin B-12 and selenium status of Dutch vegetarians compared with omnivores: a cross-sectional study. Am J Clin Nutr. 1994;60(4):683-9.
[27] Krajcovicova-Kudlackova M, Simoncic R, Béderova A, Babinska K, Grancicova E. Selected vitamins and trace elements in blood of vegetarians. Ann Nutr Metab. 1995;39(2):76-81.
[28] Lombard J, et al. Plasma selenium in French vegetarians and meat-eaters. Biol Trace Elem Res. 1996;52(1):21-31.
[29] Chaudhary SC, et al. Association of Dietary and Serum Selenium with Bone Mineral Density among US Adults: National Health and Nutrition Examination Survey, 2011-2016. Nutrients. 2021;13(1):260.
[30] Carter RC, et al. Serum selenium, race, and prostate cancer risk. J Urol. 2009;181(4):1604-10.
[31] Fair AM, et al. Predictors of serum selenium in the United States: data from the Third National Health and Nutrition Examination Survey. Biol Trace Elem Res. 2007;116(1):9-22.
[32]жать P, et al. Serum micronutrient concentrations and the prevalence of hypertension in US adults. J Nutr Health Aging. 2012;16(7):639-45.
[33] Okubo H, et al. Associations of dietary and blood selenium with cognitive function in Japanese community-dwelling older adults. Nutrients. 2022;14(24):5316.
[34] Falandysz J. Selenium in the marine environment and biota: a review. Sci Total Environ. 1994;145(1-2):1-11.
[35] Yang Q, et al. Geographic distribution of selenium level and related factors in soil of China. Environ Geochem Health. 2020;42(2):429-37.
[36] Tinggi U. Selenium: its role as antioxidant in human health. Environ Health Prev Med. 2008;13(2):102-8.
[37] Ren J, Wu G, Li A, et al. Keshan disease: a case study of an endemic deficiency-related disease. Chin Med J (Engl). 2017;130(10):1207-11
